Hypertension, or high blood pressure, is a life-threatening condition that affects over 60 million North American adults. Hypertension is defined as a systolic pressure exceeding 140 mm mercury (Hg) and exceeding 90 mm Hg, diastolic pressure. Many people with hypertension display "white coat syndrome", a conditioned response of the autonomic nervous system to increase blood pressure during anxiety.

This group of 28 participants were neither depressed nor anxious. They were given sub-delta AVE and alpha AVE. Surprisingly, sub-delta AVE produced a drop in systolic of 20 mm Hg and diastolic pressure by 16 mm Hg. On average, the best medical treatment (using multiple meds) produces a drop of 16 mm Hg.